Frontiers | A Trigger for Opioid Misuse: Chronic Pain and Stress Dysregulate the Mesolimbic Pathway and Kappa Opioid System
Opioids to Treat Depression: The Jury Is Out
Endogenous opioid system dysregulation in depression: implications for new therapeutic approaches | Molecular Psychiatry
The Role of Dynorphin and the Kappa Opioid Receptor in Schizophrenia and Major Depressive Disorder: A Translational Approach | SpringerLink
Role of kappa-opioid receptors in stress and anxiety-related behavior. - Abstract - Europe PMC
Scientists Take a Big Step toward Building a Better Opioid | Newsroom
Frontiers | The Role of the Kappa Opioid System in Comorbid Pain and Psychiatric Disorders: Function and Implications
κ Opioid Receptor-Dynorphin Signaling in the Central Amygdala Regulates Conditioned Threat Discrimination and Anxiety | eNeuro
Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience
Opioid receptor modulation of neural circuits in depression: What can be learned from preclinical data? - ScienceDirect
κ-opioid receptor - Wikipedia
J Clin Med Res
Frontiers Publishing Partnerships | Mechanisms Underlying the Anti-Suicidal Treatment Potential of Buprenorphine
Lowered endogenous mu-opioid receptor availability in subclinical depression and anxiety | Neuropsychopharmacology
Frontiers | Traumatic Stress-Induced Vulnerability to Addiction: Critical Role of the Dynorphin/Kappa Opioid Receptor System
A Systematic Review on the Kappa Opioid Receptor and Its Ligands: New Directions for the Treatment of Pain, Anxiety, Depression, and Drug Abuse | Biological and Medicinal Chemistry | ChemRxiv | Cambridge Open Engage
Figure 4 | A Narrative Pharmacological Review of Buprenorphine: A Unique Opioid for the Treatment of Chronic Pain | SpringerLink
In major depression, increased kappa and mu opioid receptor levels are associated with immune activation | Acta Neuropsychiatrica | Cambridge Core
Development of κ opioid receptor antagonists. | Semantic Scholar
Opioid receptor modulation of neural circuits in depression: What can be learned from preclinical data? - ScienceDirect
Kappa Opioid System in Nucleus Accumbens Drives Pain-Induced Negative Affect | Pain Research Forum
Dynorphin, stress, and depression | Semantic Scholar
Opioid receptor modulation of neural circuits in depression: What can be learned from preclinical data? - ScienceDirect
Kappa Opioid Receptor Ligands and Pharmacology: Diphenethylamines, a Class of Structurally Distinct, Selective Kappa Opioid Ligands | SpringerLink
Opioid receptors: distinct roles in mood disorders - ScienceDirect
